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Invitrogen™ SFRS4 Polyclonal Antibody
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Catalog No. PIPA5113702
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100 μL
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PIPA5113702 100 μL
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Catalog No. PIPA5113702 Supplier Invitrogen™ Supplier No. PA5113702
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RSREESRSRS RSRSKSERSR KRGSKRDSKA GSSKKKKKED TDRSQSRSPS For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Dog: 93%; Human: 100%; Pig: 86%; Rat: 86%.

Serine/arginine-rich protein 75 (SRp75) is encoded by the SRSF4 gene. SRp75 belongs to the arginine/serine-rich factor family and likely plays a role in alternative mRNA splicing.The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/ serine (RS)-rich domain. They are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport. The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing sites.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SFRS4
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SRSF4
Gene Accession No. Q08170
Gene Alias 5730499P16Rik; AW550192; MNCb-2616; Pre-mRNA-splicing factor SRP75; RGD1561347; serine and arginine rich splicing factor 4; serine/arginine-rich splicing factor 4; SFRS4; splicing factor, arginine/serine-rich 4; splicing factor, arginine/serine-rich 4 (SRp75); SR splicing factor 4; SRP001LB; SRP75; SRSF4
Gene Symbols SRSF4
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human SFRS4.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6429
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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