Invitrogen™ SFRS4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113702

Catalog No. PIPA5113702

Description

Immunogen sequence: RSREESRSRS RSRSKSERSR KRGSKRDSKA GSSKKKKKED TDRSQSRSPS For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Dog: 93%; Human: 100%; Pig: 86%; Rat: 86%.

Serine/arginine-rich protein 75 (SRp75) is encoded by the SRSF4 gene. SRp75 belongs to the arginine/serine-rich factor family and likely plays a role in alternative mRNA splicing.The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/ serine (RS)-rich domain. They are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport. The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing sites.

Specifications

• Antigen: SFRS4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRSF4
• Gene Alias: 5730499P16Rik; AW550192; MNCb-2616; Pre-mRNA-splicing factor SRP75; RGD1561347; serine and arginine rich splicing factor 4; serine/arginine-rich splicing factor 4; SFRS4; splicing factor, arginine/serine-rich 4; splicing factor, arginine/serine-rich 4 (SRp75); SR splicing factor 4; SRP001LB; SRP75; SRSF4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6429
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q08170
• Gene Symbols: SRSF4
• Immunogen: Synthetic peptide directed towards the middle region of human SFRS4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov