Invitrogen™ SFTPC Monoclonal Antibody (5E6A9)

Catalog No.	Quantity
PIMA517172	100 μg

Catalog No. PIMA517172 Supplier Invitrogen™ Supplier No. MA517172

Description

Mouse Monoclonal Antibody

MA5-17172 targets SFTPC in indirect ELISA and WB applications and shows reactivity with Human samples. The MA5-17172 immunogen is purified recombinant fragment of human SFTPC (amino acids: 60-180 ) expressed in E. Coli. MA5-17172 detects SFTPC which has a predicted molecular weight of approximately 21kDa.

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Specifications

• Antigen: SFTPC
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 5E6A9
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% sodium azide
• Gene: Sftpc
• Gene Accession No.: P11686
• Gene Alias: BRICD6; BRICHOS domain containing 6; LOW QUALITY PROTEIN: pulmonary surfactant-associated protein C; pro-SpC; PSP C; PSP-C; pulmonary surfactant apoprotein-2 SP-C; pulmonary surfactant associated protein C; pulmonary surfactant protein C; pulmonary surfactant-associated protein C; Pulmonary surfactant-associated proteolipid SPL(Val); SFTP 2; SFTP2; Sftp-2; Sftpc; SMDP2; SP C; SP5; SPC; SP-C; surfactant associated protein C; surfactant protein C; Surfactant pulmonary-associated protein C; Surfactant, pulmonary-associated protein C; surfactant-associated protein; type I SP-C; type I surfactant protein C; type II SP-C; type II surfactant protein C
• Gene Symbols: Sftpc
• Host Species: Mouse
• Immunogen: Purified recombinant fragment of human SFTPC (amino acids: 60-180 ) expressed in E. Coli.
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6440
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1