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  5. R&D Systems™ SGC 6870

R&D Systems™ SGC 6870
SDP

Catalog No. RD10195115 Shop All Novus Products
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25 mg
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RD10195115 25 mg
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Catalog No. RD10195115 Supplier R&D Systems™ Supplier No. 7182/25

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Description

A Tocris product, part of R&D Systems. Potent and selective PRMT6 allosteric inhibitor

SGC 6870 is a potent and selective protein arginine methyltransferase 6 (PRMT6) allosteric inhibitor (IC50 = 77 nM). Exhibits selectivity over all other PRMTs and 23 methyltransferases. In HEK293T cells overexpressing PRMT6, inhibits asymmetric dimethylation of H3R2 (IC50 = 0.8 μM) Negative control SGC 6870N (Cat. No. 7184) also available.

Specifications

Chemical Name or Material (R)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
CAS 2561471-27-8
Quantity 25 mg
Product Line Tocris
Target Protein Arginine Methyltransferase Inhibitors
Molecular Formula C23H21BrN2O2S
Purity 0.98
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