Invitrogen™ SGCE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530720

Catalog No. PIPA530720

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (94%), Pig (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SGCE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGCE
• Gene Alias: dystonia 11, myoclonic; DYT11; EMBL:AAO37579.1, ECO:0000312; EMBL:AAO37579.1}; Epsilon sarcoglycan; Epsilon SG; Epsilon-sarcoglycan; epsilon-sarcoglycan {ECO:0000312; epsilon-SG; epsilon-SG {ECO:0000250; ESG; e-SG; RGD:1303201}; sarcoglycan; sarcoglycan epsilon; sarcoglycan, epsilon; SGCE; sgce {ECO:0000312; UniProtKB:O43556}; UNQ433/PRO840
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20392, 8910
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O43556, O70258
• Gene Symbols: SGCE
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 232 of Human SGCE.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG