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  5. Tocris Bioscience™ SGI 1027

Tocris Bioscience™ SGI 1027

Catalog No. 515550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

DNA methyltransferase inhibitor

SGI 1027 is a DNA methyltransferase inhibitor. Inhibits the mammalian DNA methyltransferases DNMT3B, DNMT3A and DNMT1 (IC50 values are 7.5, 8 and 12.5 μM with Poly(dl-dC) as the substrate). Reactivates silenced tumor suppressor genes by reducing CpG island hypermethylation.

Specifications

Purity >99%
Quantity 50 mg
Product Type SGI 1027
Molecular Weight (g/mol) 461.52
Inhibitors SGI 1027

For Research Use Only

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