Invitrogen™ SGK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579992

Catalog No. PIPA579992

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HEPG2 whole cell.

SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.

Specifications

• Antigen: SGK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGK1
• Gene Alias: serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6446
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: O00141
• Gene Symbols: SGK1
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SGK1 (28-55aa MKQRRMGLNDFIQKIANNSYACKHPEVQ).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov