Invitrogen™ SGK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA586236

Catalog No. PIPA586236

Description

Purity is > 95% by SDS-PAGE.

SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.

Specifications

• Antigen: SGK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGK1
• Gene Alias: serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20393, 29517, 6446
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O00141, Q06226, Q9WVC6
• Gene Symbols: SGK1
• Immunogen: Synthetic peptide, corresponding to amino acids 391-431 of Human SGK1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov