SGMS1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA112761

Catalog No. 01-675-783

Description

A suggested positive control for this product is brain, heart, kidney, liver, muscle or stomach lysate.

A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.

Specifications

• Antigen: SGMS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGMS1
• Gene Alias: 9530058O11Rik; AI841905; C80702; hmob33; Medulla oblongata-derived protein; MGC17342; MOB; MOB1; mob-1; Phosphatidylcholine:ceramide cholinephosphotransferase 1; protein Mob; SGMS1; SMS1; Sor1; sphingomyelin synthase 1; TMEM23; Transmembrane protein 23
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 208449, 259230
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: Q86VZ5, Q8VCQ6
• Gene Symbols: SGMS1
• Immunogen: Synthetic peptide corresponding to human sphingomyelin synthase 1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov