Invitrogen™ SGMS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA526744

Catalog No. PIPA526744

Description

This antibody is predicted to react with non-human primate and rat based on sequence homology.

A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.

Specifications

• Antigen: SGMS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGMS2
• Gene Alias: 4933405A16Rik; 5133401H06Rik; AI854299; MGC26963; phosphatidylcholine:ceramide cholinephosphotransferase 2; RGD1305778; SGMS2; SM synthase; SMS2; spermatin; Sphingomyelin synthase 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 166929, 74442
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q8NHU3, Q9D4B1
• Gene Symbols: SGMS2
• Immunogen: KLH conjugated synthetic peptide between 338-365 amino acids from the C-terminal region of human SGMS2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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