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SGO2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501559920
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50-155-9920 20 μL
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Catalog No. 50-155-9920 Supplier Bethyl Laboratories, Inc Supplier No. A301262AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation. Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

Specifications

Antigen SGO2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SGO2
Gene Accession No. Q562F6
Gene Alias SGOL2; Shugoshin-like 2; Shugoshin-2; Tripin
Gene Symbols SGO2
Host Species Rabbit
Immunogen Between 750 and 800
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151246
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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