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Invitrogen™ SGPP2 Polyclonal Antibody
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Catalog No. PIPA542767
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100 μL
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PIPA542767 100 μL
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Catalog No. PIPA542767 Supplier Invitrogen™ Supplier No. PA542767
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Rabbit Polyclonal Antibody

Peptide sequence: SKPAESLPVI QNIPPLTTYM LVLGLTKFAV GIVLILLVRQ LVQNLSLQVL Sequence homology: Cow: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 85%.

Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/Gprotein- coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. SPPase2 is localized to the endoplasmic reticulum. The enzymatic activity and localization of SPPase2 are similar to SPPase1. The tissue expression of SPPase2 was different from that of SPPase1. SPPase2 is an important member of the SPPase family whichplay a role in attenuating intracellular S1P signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SGPP2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SGPP2
Gene Accession No. Q8IWX5
Gene Alias FLJ39004; RGD1565739; SGPP2; sphingosine 1-phosphate phosphohydrolase 2; sphingosine-1-phosphatase 2; Sphingosine-1-phosphate phosphatase 2; sphingosine-1-phosphate phosphotase 2; Spp2; SPPase2
Gene Symbols SGPP2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human SGPP2 (aa 301-350).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 130367
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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