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Invitrogen™ SGSH Polyclonal Antibody
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Catalog No. PIPA596950
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100 μL
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PIPA596950 100 μL
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Catalog No. PIPA596950 Supplier Invitrogen™ Supplier No. PA596950
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DNGIPFPSGR TNLYWPGTAE PLLVSSPEHP KRWGQVSEAY VSLLDLTPTI LDWFSIPYPS YAIFGSKTIH LTGRSLLPAL EAEPLWATVF GSQSHHEVTM SYPMRSVQHR HFRLVHNLNF KMPFPIDQDF YVSPTFQDLL NRTTAGQPTG WYKDLRHYYY RARWELYDRS RDPHETQNLA TDPRFAQLLE MLRDQLAKWQ WETHDPWVCA PDGVLEEKLS PQCQPLHNEL; Positive Samples: MCF7, 22Rv1, HepG2, Mouse liver, Mouse testis; Cellular Location: Lysosome.

SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SGSH
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.79 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene SGSH
Gene Accession No. P51688
Gene Alias 4632406A19Rik; heparan sulfate sulfamidase; heparan sulfate sulfatase; HSS; MPS3A; mucopolysaccharidosis type IIIA; N-sulfoglucosamine sulfohydrolase; N-sulfoglucosamine sulfohydrolase (sulfamidase); N-sulphoglucosamine sulphohydrolase; SFMD; SGSH; Sulfoglucosamine sulfamidase; sulphamidase
Gene Symbols SGSH
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 273-502 of human SGSH (NP_0001901).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27029, 6448, 688293
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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