Invitrogen™ SGSM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552038

Catalog No. PIPA552038

Description

Immunogen sequence: SPDSGHPSSH NFSSGLSEHS EPSLSTEDSV LDAQRNTPTV LRPRDGSVDD RQSSEATTSQ DEAPREELAV QDSLESDLLA NESMDEFMSI TGSLDMALPE KDDVVMEGWR SSETEKHGQA DSEDNLSEEP EMESLFPALA SLAVTT Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.

Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1, 148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.

Specifications

• Antigen: SGSM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGSM1
• Gene Alias: 2410098H20Rik; AA408781; D5Bwg1524e; E130107M15; KIAA1941; NuIP; nurr1-interacting protein; RUN and TBC1 domain containing 2; RUN and TBC1 domain-containing protein 2; RUTBC2; SGSM1; Small G protein signaling modulator 1; small G protein signaling modulator 1 protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 129049
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q2NKQ1
• Gene Symbols: SGSM1
• Immunogen: Recombinant protein corresponding to Human SGSM1. Recombinant protein control fragment (Product #RP-91520).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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