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Invitrogen™ SH3BP1 Polyclonal Antibody
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Catalog No. PIPA581891
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100 μL
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Catalog No. Quantity
PIPA581891 100 μL
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Catalog No. PIPA581891 Supplier Invitrogen™ Supplier No. PA581891
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ENLSNLRYLM KFLARLAEEQ EVNKMTPSNI AIVLGPNLLW PPEKEGDQAQ LDAASVSSIQ VVGVVEALIQ SADTLFPGDI NFNVSGLFSA VTLQDTVSDR LASEELPSTA VPTPATTPAP APAPAPAPAP ALASAATKER TESEVPP Highest antigen sequence indentity to the following orthologs: Rat - 74%, Mouse - 75%.

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SH3BP1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SH3BP1
Gene Accession No. Q9Y3L3
Gene Alias 3bp1; 3BP-1; ARHGAP43; OTTHUMP00000028981; SH3 domain binding protein 1; SH3 domain-binding protein 1; SH3BP1; SH3-domain binding protein 1
Gene Symbols SH3BP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SH3BP1. Recombinant protein control fragment (Product #RP-91341).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23616
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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