Invitrogen™ SH3BP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587739

Catalog No. PIPA587739

Description

Immunogen sequence: VPEAMARPAV LPRPEKPQLP HLQRSPPDGQ SFRSFSFEKP RQPSQADTGG DDSDEDYEKV PLPNSVFVNT TESCEVERLF KATSPRGEPQ DGLYCIRNSS TKSGKVLVVW DETSNKVRNY RIFEKDSKFY LEGEVLFVSV GSMVEHYHTH VLPSHQSLLL RHPYGYTGPR; Positive Samples: A549, Mouse spleen, Mouse lung.

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SH3BP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sh3bp2
• Gene Alias: 3BP2; 3BP-2; Abl-SH3 binding protein 2; CRBM; CRPM; FLJ42079; LOW QUALITY PROTEIN: SH3 domain-binding protein 2; RES4-23; SH3 domain binding protein 2; SH3 domain-binding protein 2; SH3BP2; SH3-domain binding protein 2; TNFAIP3 interacting protein 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24055, 6452
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P78314, Q06649
• Gene Symbols: Sh3bp2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_0011161531).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG