Invitrogen™ SH3BP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529031

Catalog No. PIPA529031

Description

Recommended positive controls: A431, HeLa, HepG2, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SH3BP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sh3bp2
• Gene Alias: 3BP2; 3BP-2; Abl-SH3 binding protein 2; CRBM; CRPM; FLJ42079; LOW QUALITY PROTEIN: SH3 domain-binding protein 2; RES4-23; SH3 domain binding protein 2; SH3 domain-binding protein 2; SH3BP2; SH3-domain binding protein 2; TNFAIP3 interacting protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6452
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P78314
• Gene Symbols: Sh3bp2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human 3BP2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov