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Invitrogen™ SH3BP4 Polyclonal Antibody
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Catalog No. PIPA544269
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100 μL
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PIPA544269 100 μL
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Catalog No. PIPA544269 Supplier Invitrogen™ Supplier No. PA544269
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Rabbit Polyclonal Antibody

Peptide sequence: FTTLKFSKGD HLYVLDTSGG EWWYAHNTTE MGYIPSSYVQ PLNYRNSTLS Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SH3BP4
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SH3BP4
Gene Accession No. Q9P0V3
Gene Alias AI594717; AW227605; BOG25; EHB10; EH-binding protein 10; SH3 domain binding protein 4; SH3 domain-binding protein 4; SH3 domain-binding protein 4; SH3-domain binding protein 4; Sh3bp4; SH3-domain binding protein 4; si:dkey-57b6.3; Transferrin receptor-trafficking protein; TTP
Gene Symbols SH3BP4
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human SH3BP4 (aa 71-120).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23677
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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