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Invitrogen™ SH3BP4 Polyclonal Antibody
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Catalog No. PIPA557993
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100 μL
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PIPA557993 100 μL
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Catalog No. PIPA557993 Supplier Invitrogen™ Supplier No. PA557993
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LKVCMFSNMT NYEVKASEQA KVVRGFQLKL GKVSRLIFPI TSQNPNELSD FTLRVQVKDD QEAILTQFCV QTPQPPPKSA IKPSGQRRFL KKNEVGKIIL Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SH3BP4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SH3BP4
Gene Accession No. Q9P0V3
Gene Alias AI594717; AW227605; BOG25; EHB10; EH-binding protein 10; SH3 domain binding protein 4; SH3 domain-binding protein 4; SH3 domain-binding protein 4; SH3-domain binding protein 4; Sh3bp4; SH3-domain binding protein 4; si:dkey-57b6.3; Transferrin receptor-trafficking protein; TTP
Gene Symbols SH3BP4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SH3BP4. Recombinant protein control fragment (Product #RP-102773).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23677
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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