SH3PXD2A Mouse anti-Human, Clone: OTI1F5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811757

Catalog No. 50-167-0828

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

Specifications

• Antigen: SH3PXD2A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: SH3PXD2A
• Gene Alias: FISH, SH3MD1, TKS5
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9644
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI1F5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q5TCZ1
• Gene Symbols: SH3PXD2A
• Immunogen: Human recombit protein fragment corresponding to amino acids 299-395 of human SH3PXD2A produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1