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Invitrogen™ SH3PXD2A Polyclonal Antibody
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Catalog No. PIPA5142568
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100 μg
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PIPA5142568 100 μg
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Catalog No. PIPA5142568 Supplier Invitrogen™ Supplier No. PA5142568
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Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SH3PXD2A
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Sh3pxd2a
Gene Accession No. Q5TCZ1
Gene Alias 2310014D11Rik; AA589508; Adapter protein TKS5; adaptor protein TKS5; AI256723; AI413738; C230050L11; EG329070; FISH; Five SH3 domain-containing protein; five SH3 domains; Gm5098; KIAA0418; SH3 and PX domain-containing protein 2A; SH3 and PX domains 2A; SH3 multiple domains 1; SH3 multiple domains protein 1; Sh3md1; SH3PXD2A; Tks5; TSK5; Tyrosine kinase substrate with five SH3 domains
Gene Symbols Sh3pxd2a
Host Species Goat
Immunogen Peptide with sequence C-KPIEKSQFIHNNLK.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9644
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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