Invitrogen™ SH3PXD2A Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142568

Catalog No. PIPA5142568

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

Specifications

• Antigen: SH3PXD2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sh3pxd2a
• Gene Alias: 2310014D11Rik; AA589508; Adapter protein TKS5; adaptor protein TKS5; AI256723; AI413738; C230050L11; EG329070; FISH; Five SH3 domain-containing protein; five SH3 domains; Gm5098; KIAA0418; SH3 and PX domain-containing protein 2A; SH3 and PX domains 2A; SH3 multiple domains 1; SH3 multiple domains protein 1; Sh3md1; SH3PXD2A; Tks5; TSK5; Tyrosine kinase substrate with five SH3 domains
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 9644
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q5TCZ1
• Gene Symbols: Sh3pxd2a
• Immunogen: Peptide with sequence C-KPIEKSQFIHNNLK.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG