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Invitrogen™ SHANK1 Monoclonal Antibody (M369)
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Catalog No. PIMA547733
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100 μL
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Catalog No. Quantity
PIMA547733 100 μL
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Catalog No. PIMA547733 Supplier Invitrogen™ Supplier No. MA547733
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Description

Mouse Monoclonal Antibody

This antibody detects a 225 kDa* protein corresponding to the molecular mass of Shank1 on SDS-PAGE immunoblots of adult mouse brain.

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SHANK1
Applications Western Blot
Classification Monoclonal
Clone M369
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene SHANK1
Gene Accession No. D3YZU1, Q9WV48, Q9Y566
Gene Alias GKAP/SAPAP interacting protein; GKAP/SAPAP-interacting protein; OTTHUMP00000174437; SAPAP-interacting protein synamon; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; SHANK 1; Shank1; Shank1a; somatostatin receptor-interacting protein; SPANK 1; Spank1; SPANK-1; SSTR-interacting protein; Sstrip; Synamon
Gene Symbols SHANK1
Host Species Mouse
Immunogen Clone M369 was generated from a sequence corresponding to amino acids in the C-terminal region of rat Shank1. This sequence has high homology to human and mouse Shank1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 243961, 50944, 78957
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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