SHANK2 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-1196	100 μL

Catalog No. 50-198-1196 Supplier Bioss Supplier No. BS11238R

Description

Rabbit Polyclonal Antibody

This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: SHANK2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: SHANK2
• Gene Accession No.: Q9UPX8
• Gene Alias: AUTS17; cortactin SH3 domain-binding protein; Cortactin-binding protein 1; Cortbp1; CORTBP1CTTNBP1; CTTNBP1; GKAP/SAPAP interacting protein; GKAP/SAPAP-interacting protein; KIAA1022; mKIAA1022; proline rich synapse associated protein 1; proline-rich synapse associated protein 1; Proline-rich synapse-associated protein 1; PROSAP1; SH3 and multiple ankyrin repeat domains 2; SH3 and multiple ankyrin repeat domains protein 2; SH3/ankyrin domain gene 2; SHANK; Shank2; SPANK-3
• Gene Symbols: SHANK2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human SHANK2.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22941
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG