GDNF, Sheep, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-117-012	50 μg

Catalog No. 89-117-012 Supplier Abnova Corporation Supplier No. PAB14339

Description

Sheep polyclonal antibody raised against recombinant GDNF.

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq

Specifications

• Antigen: GDNF
• Applications: Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Sheep polyclonal antibody raised against recombinant GDNF.
• Dilution: Immunohistochemistry (1 ug/mL) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from PBS
• Gene: GDNF
• Gene Alias: ATF1/ATF2/HFB1-GDNF
• Gene Symbols: GDNF
• Host Species: Sheep
• Immunogen: Recombinant protein corresponding to human GDNF.
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2668
• Test Specificity: No cross reactivity with NTN has been observed in western blot analysis.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized

For Research Use Only