IL10, Sheep, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-634	1 mL

Catalog No. 89-133-634 Supplier Abnova Corporation Supplier No. PAB8408

Description

Sheep polyclonal antibody raised against partial length recombinant IL10.

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq

Specifications

• Antigen: IL10
• Applications: ELISA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Sheep polyclonal antibody raised against partial length recombinant IL10.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In 20mM phosphate buffer, 150mM NaCl, pH 7.2 (0.09% sodium azide)
• Gene: IL10
• Gene Alias: CSIF/IL-10/IL10A/MGC126450/MGC126451/TGIF
• Gene Symbols: IL10
• Host Species: Sheep
• Immunogen: Recombinant His fusion protein corresponding to amino acids 19-178 of human IL10.
• Quantity: 1 mL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3586
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only