S100B, Sheep, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-662	1 mL

Catalog No. 89-133-662 Supplier Abnova Corporation Supplier No. PAB8439

Description

Sheep polyclonal antibody raised against partial length recombinant S100B.

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq]

Specifications

• Antigen: S100B
• Applications: ELISA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Sheep polyclonal antibody raised against partial length recombinant S100B.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In 20mM phosphate buffer, 150mM NaCl, pH 7.2 (0.09% sodium azide)
• Gene: S100B
• Gene Alias: NEF/S100/S100beta
• Gene Symbols: S100B
• Host Species: Sheep
• Immunogen: Recombinant His fusion protein corresponding to amino acids 2-92 of human S100B.
• Quantity: 1 mL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6285
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only