SNCA Sheep anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-395	100 μL

Catalog No. 89-114-395 Supplier Abnova Corporation Supplier No. PAB0750

Description

Sheep polyclonal antibody raised against synthetic peptide of SNCA.

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq]

Sequence: CMPVDPDNEAYEMPSEE

Specifications

• Antigen: SNCA
• Applications: Immunohistochemistry (Frozen)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Sheep polyclonal antibody raised against synthetic peptide of SNCA.
• Dilution: Immunohistochemistry (1:1000-1:2000) The optimal working dilutions must be determined by the end user.
• Formulation: Lyophilized from PBS
• Gene: SNCA
• Gene Alias: MGC110988/NACP/PARK1/PARK4/PD1
• Gene Symbols: SNCA
• Host Species: Sheep
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 116-131 of human SNCA.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6622
• Test Specificity: Immunohistochemistry shows a high specificity for alpha-synuclein.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized

For Research Use Only