TFPI, Sheep, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-335	1 mg

Catalog No. 89-114-335 Supplier Abnova Corporation Supplier No. PAB0682

Description

Sheep polyclonal antibody raised against a C-terminal truncated recombinant TFPI molecule comprised of domains 1 and 2.

This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq

Specifications

• Antigen: TFPI
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Sheep polyclonal antibody raised against a C-terminal truncated recombinant TFPI molecule comprised of domains 1 and 2.
• Dilution: Western Blot (25 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol)
• Gene: TFPI
• Gene Alias: EPI/LACI/TFI/TFPI1
• Gene Symbols: TFPI
• Host Species: Sheep
• Immunogen: Recombinant protein corresponding to C-terminus truncated TFPI molecule comprised of regions 1 and 2.
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7035
• Test Specificity: This antibody recognizes human tissue factor pathway inhibitor.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only