Invitrogen™ Shiga toxin 2B Monoclonal Antibody (08)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528963

Catalog No. PIMA528963

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Enterohemorrhagic E. coli (EHEC) stx2B/Shiga toxin II subunit B.

Shiga-like toxin (verotoxin) is a toxin produced by some strains of Escherichia coli. Shiga-like toxin is named for its similarity to the AB5-type Shiga toxin produced by the bacteria Shigella dysenteriae. There are two known types-SLT1 and SLT2. The Shiga-like toxin is linked with hemolytic-uremic syndrome. Shiga-like toxin requires highly specific receptors on the cells' surface in order to attach and enter the cell. Species such as cattle, swine, and deer which do not carry these receptors may harbor toxigenic bacteria without any ill effect, dropping them in their feces, from where they may be distributed to humans. Shiga Like Toxin-2 Subunit B has nontoxic action, it is the functional region which binds to the receptor. Upon binding to the host cell receptor, the Shiga Like Toxin-2 Subunit B forms a pentamer. The Shiga Like Toxin-2 Subunit B can be useful in vaccine study, antibody test and other functional research.

Specifications

• Antigen: Shiga toxin 2B
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody

• Applications: ELISA
• Clone: 08
• Conjugate: Unconjugated
• Gene Alias: Shiga toxin; Shigatoxin Type 2; Shigatoxin Type II; STX2; STX-2b; STX-IIb
• Immunogen: Recombinant Enterohemorrhagic E. coli (EHEC) stx2B/Shiga toxin II subunit B Protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid