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Tocris Bioscience™ SHIN 1
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Catalog No. 69985
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69-985 5 mg
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Catalog No. 69-985 Supplier Tocris Bioscience™ Supplier No. 6998/5
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Description

Potent SHMT inhibitor

SHIN 1 is a potent serine hydroxymethyltransferase (SHMT) inhibitor (IC50 values are 5 and 13 nM at SHMT1 and SHMT2, respectively). Inhibits growth of HCT-116 cells in vitro (IC50 = 870 nM). Unstable in liver microsome assays.

Specifications

Chemical Name or Material 6-Amino-1,4-dihydro-4-[5-(hydroxymethyl)[1,1-biphenyl]-3-yl]-3-methyl-4-(1-methylethyl)pyrano[2,3-c]pyrazole-5-carbonitrile
CAS 2146095-85-2
Quantity 5 mg
Target Other Transferase Inhibitors
Molecular Formula C24H24N4O2
Formula Weight 3081
Purity 98%
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