Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA563631

Invitrogen™ SHISA7 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA563631
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA563631 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA563631 Supplier Invitrogen™ Supplier No. PA563631
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: VGAKVAFSKA SRAPRAHRDI NVPRALVDIL RHQA Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

The SHISA7 gene encodes a member of the Shisa family proteins, which are involved in the regulation of signaling pathways critical for embryonic development and cellular communication. SHISA7 is particularly influential in modulating synaptic transmission in the central nervous system. It plays a key role in regulating the surface expression and activity of AMPA-type glutamate receptors, which are crucial for fast excitatory neurotransmission and synaptic plasticity in the brain. By controlling the trafficking and localization of these receptors, SHISA7 impacts synaptic strength and neuronal excitability, affecting learning, memory, and other cognitive functions. The functional regulation by SHISA7 of AMPA receptors can have implications for neuropsychiatric disorders, where dysregulation of synaptic transmission is a common feature. Understanding SHISA7's role in synaptic modulation could lead to insights into the mechanisms underlying cognitive processes and the development of therapeutic strategies for neurological conditions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SHISA7
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SHISA7
Gene Accession No. A6NL88
Gene Alias CKAMP59; Cystine-knot AMPAR modulating protein of 59 kDa; hCG_2039146; Protein shisa-6-like; Protein shisa-7; shisa family member 7; shisa homolog 7; SHISA7; UPF0626 protein A
Gene Symbols SHISA7
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SHISA7. Recombinant protein control fragment (Product #RP-101586).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 729956
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.