Invitrogen™ SHKBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521731

Catalog No. PIPA521731

Description

Recommended positive controls: A431, H1299. Predicted reactivity: Mouse (96%), Rat (96%), Xenopus laevis (82%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.

Specifications

• Antigen: SHKBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SHKBP1
• Gene Alias: B930062H15Rik; PP203; RGD1309281; Sb1; SETA binding protein 1; SETA-binding protein 1; SH3KBP1 binding protein 1; SH3KBP1-binding protein 1; Shkbp1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 92799
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8TBC3
• Gene Symbols: SHKBP1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SHKBP1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov