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Invitrogen™ SHMT1 Polyclonal Antibody
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Catalog No. PIPA5140301
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100 μL
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PIPA5140301 100 μL
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Catalog No. PIPA5140301 Supplier Invitrogen™ Supplier No. PA5140301
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: LQIQSDTGVR ATLKEFKERL AGDKYQAAVQ ALREEVESFA SLFPLPGLPD F Highest antigen sequence indentity to the following orthologs: Rat - 75%, Mouse - 73%.

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SHMT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Shmt1
Gene Accession No. P34896
Gene Alias AI324848; AI385541; C81125; CSHMT; cytoplasmic serine hydroxymethyltransferase; cytosolic form; cytosolic serine hydroxymethyltransferase; glycine hydroxymethyltransferase; LRRGT00032; MEL-32; MGC15229; MGC24556; mshmt; mshmt1; mshmt2; serine hydroxymethyl transferase; serine hydroxymethyltransferase; serine hydroxymethyltransferase 1; serine hydroxymethyltransferase 1 (soluble); serine hydroxymethyltransferase 1 (soluble) isoform 1; serine hydroxymethyltransferase 2 (mitochondrial); serine hydroxymethyltransferase, cytosolic; Serine methylase; SHMT; Shmt1; shmt1 protein; SHMT2; zgc:66171; zgc:77524; zSHMT-1
Gene Symbols Shmt1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SHMT1. Recombinant protein control fragment (Product #RP-109683).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6470
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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