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SHMT2 Mouse anti-Human, Clone: OTI1E12, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF808813

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.Specifications
SHMT2 | |
Monoclonal | |
Unconjugated | |
SHMT2 | |
GLYA, HEL-S-51e, SHMT | |
Mouse | |
Affinity Chromatography | |
RUO | |
6472 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI1E12 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P34897 | |
SHMT2 | |
Full length human recombit protein of human SHMT2 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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