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SHMT2 Mouse anti-Human, Clone: OTI3E9, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA808820
SDSDocumentsProduct Certifications Promotions
DescriptionMammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|Full length human recombit protein of human SHMT2 produced in E.coli.|
|Immunohistochemistry (Paraffin), Western Blot|
|GLYA, HEL-S-51e, SHMT|
|-20° C, Avoid Freeze/Thaw Cycles|
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