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SHMT2 Mouse anti-Human, Clone: OTI3E9, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA808820
Description
Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.Specifications
| SHMT2 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P34897 | |
| SHMT2 | |
| Full length human recombit protein of human SHMT2 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI3E9 | |
| Unconjugated | |
| SHMT2 | |
| GLYA, HEL-S-51e, SHMT | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 6472 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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