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Invitrogen™ SHMT2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5121611
This item is not returnable.
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Description
SHMT2 Polyclonal Antibody for Western Blot, IHC (P)
Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.
Specifications
SHMT2 | |
Polyclonal | |
Unconjugated | |
SHMT2 | |
2700043D08Rik; AA408223; AA986903; epididymis secretory sperm binding protein Li 51e; GLY A+; GLYA; glycine auxotroph A, human complement for hamster; glycine hydroxymethyltransferase; HEL-S-51e; mitochondrial serine hydroxymethyltransferase; serine aldolase; serine hydroxymethylase; serine hydroxymethyltransferase; serine hydroxymethyltransferase 2; serine hydroxymethyltransferase 2 (mitochondrial); serine hydroxymethyltransferase, mitochondrial; Serine methylase; SHMT; SHMT 2; SHMT2; threonine aldolase | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
6472 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.39 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
P34897 | |
SHMT2 | |
Recombinant protein Serine Hydroxymethyltransferase 2, Mitochondrial. The antigen corresponds to amino acid range 30-504 of the target protein. | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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