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SHMT2 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A305351A
Description
The recommended shelf life for this product is 1 year from date of receipt.
Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.Specifications
| SHMT2 | |
| Polyclonal | |
| Unconjugated | |
| SHMT2 | |
| GLYA, SHMT, GLY A+, glycine auxotroph A, human complement for hamster, glycine hydroxymethyltransferase, serine aldolase, serine hydroxymethylase, serine hydroxymethyltransferase, mitochondrial, serine methylase, threonine aldolase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 108037, 6472 | |
| 4° C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 1 mg/ml | |
| phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
| P34897, Q9CZN7 | |
| SHMT2 | |
| Between 454 and 504 | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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