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SHMT2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 50556711 Shop All Proteintech Group Inc Products
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50-556-711 150 μL
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Catalog No. 50-556-711 Supplier Proteintech Group Inc Supplier No. 110991AP150UL
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Description

Rabbit Polyclonal Antibody

Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.

Specifications

Antigen SHMT2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene SHMT2
Gene Accession No. P34897, Q9CZN7
Gene Alias GLYA, Serine methylase, SHMT, SHMT2
Gene Symbols SHMT2
Host Species Rabbit
Immunogen SHMT2 Fusion Protein Ag1584
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108037, 299857, 6472
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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