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Invitrogen™ SHOX Polyclonal Antibody
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Catalog No. PIPA5104141
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100 μL
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PIPA5104141 100 μL
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Catalog No. PIPA5104141 Supplier Invitrogen™ Supplier No. PA5104141
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SHOX.

Homeodomain proteins (HP) are transcriptional regulators that coordinate the expression of genes involved in development, differentiation and cellular transformation. HPs are characterized by a conserved domain of 60 amino acid residues that recognize and bind a site in the regulatory region of the target gene. SHOX, a member of the bicoid subfamily of the paired homeobox family, controls fundamental aspects of growth and development and undergoes splicing resulting in two isoforms, SHOXA and SHOXB. SHOXA is expressed in skeletal muscle, placental, pancreas, heart and bone marrow fibroblast and, to a lesser extent, in kidney and lung. SHOXB is highly expressed in osteogenic cells, but not expressed in brain, kidney, liver or lung. Defects in the gene SHOXX cause Leri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD).
TRUSTED_SUSTAINABILITY

Specifications

Antigen SHOX
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SHOX
Gene Accession No. O15266
Gene Alias GCFX; growth control factor, X-linked; PHOG; Pseudoautosomal homeobox-containing osteogenic protein; short stature homeobox; short stature homeobox protein; Short stature homeobox-containing protein; SHOX; SHOXY; SS
Gene Symbols SHOX
Host Species Rabbit
Immunogen A synthesized peptide derived from human SHOX(Accession O15266), corresponding to amino acid residues Y35-F85.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6473
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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