Invitrogen™ SHOX2 Polyclonal Antibody

Catalog No.	Quantity
PIPA5114126	100 μL

Catalog No. PIPA5114126 Supplier Invitrogen™ Supplier No. PA5114126

Description

Rabbit Polyclonal Antibody

Immunogen sequence: PGSPRLTEVS PELKDRKEDA KGMEDEGQTK IKQRRSRTNF TLEQLNELER For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rat: 100%.

SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.

Specifications

• Antigen: SHOX2
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene: SHOX2
• Gene Accession No.: O60902
• Gene Alias: 6330543G17Rik; Homeobox protein Og12X; OG12; OG-12; Og12x; OGI2X; Paired family homeodomain protein Prx3; paired-related homeobox protein SHOT; Prx3; short stature homeobox 2; short stature homeobox protein 2; SHOT; SHOX homologous gene on chromosome 3; Shox2; similar to short stature homeobox 2; zgc:65884; zgc:77344
• Gene Symbols: SHOX2
• Host Species: Rabbit
• Immunogen: Synthetic peptide directed towards the middle region of human SHOX2.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6474
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov