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SHROOM1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983117
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100 μL
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50-198-3117 100 μL
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Catalog No. 50-198-3117 Supplier Bioss Supplier No. BS13735R
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Rabbit Polyclonal Antibody

SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.

Specifications

Antigen SHROOM1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SHROOM1
Gene Accession No. Q2M3G4
Gene Alias Apical protein 2; Apx; APXL2; KIAA1960; Protein Shroom1; RGD1308066; Shrm1; Shroom; shroom family member 1; SHROOM1
Gene Symbols SHROOM1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human SHROOM1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 134549
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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