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Invitrogen™ SIAH1 Polyclonal Antibody
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Catalog No. PIPA585202
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100 μL
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Catalog No. Quantity
PIPA585202 100 μL
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Catalog No. PIPA585202 Supplier Invitrogen™ Supplier No. PA585202
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Rat (100%), Zebrafish (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Positive Control: Synthetic peptide: 1:8,000. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that is a member of the seven in absentia homolog family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIAH1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene SIAH1
Gene Accession No. P61092, Q06985, Q8IUQ4
Gene Alias AA960570; AA982064; AI853500; E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase SIAH1A; E3 ubiquitin-protein ligase SIAH1B; FLJ08065; h HUMSIAH; hSIAH1; HUMSIAH; mSiah-1a; RING-type E3 ubiquitin transferase SIAH1; RING-type E3 ubiquitin transferase SIAH1A; RING-type E3 ubiquitin transferase SIAH1B; seven in absentia 1A; seven in absentia 1B; seven in absentia homolog 1; Seven in absentia homolog 1a; Seven in absentia homolog 1b; SIAH; siah E3 ubiquitin protein ligase 1; SIAH1; siah-1; Siah1a; Siah-1a; Siah1b; siah-1b; Sinh1a; Sinh1b
Gene Symbols SIAH1, Siah1a, Siah1b
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SIAH1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110337437, 20437, 20438, 6477
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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