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Invitrogen™ SIAH1 Polyclonal Antibody, Biotin
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Catalog No. PIPA5141996
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100 μg
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PIPA5141996 100 μg
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Catalog No. PIPA5141996 Supplier Invitrogen™ Supplier No. PA5141996
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Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize both reported isoforms (NP_003022.3; NP_001006611.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

This gene encodes a protein that is a member of the seven in absentia homolog family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIAH1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Biotin
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene SIAH1
Gene Accession No. P61092, Q06985, Q8IUQ4, Q920M9
Gene Alias AA960570; AA982064; AI853500; E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase SIAH1A; E3 ubiquitin-protein ligase SIAH1B; FLJ08065; h HUMSIAH; hSIAH1; HUMSIAH; mSiah-1a; RING-type E3 ubiquitin transferase SIAH1; RING-type E3 ubiquitin transferase SIAH1A; RING-type E3 ubiquitin transferase SIAH1B; seven in absentia 1A; seven in absentia 1B; seven in absentia homolog 1; Seven in absentia homolog 1a; Seven in absentia homolog 1b; SIAH; siah E3 ubiquitin protein ligase 1; SIAH1; siah-1; Siah1a; Siah-1a; Siah1b; siah-1b; Sinh1a; Sinh1b
Gene Symbols SIAH1, Siah1a, Siah1b
Host Species Goat
Immunogen Peptide with sequence SRQTATALPTGTSKC (aa 2-16).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110337437, 140941, 20437, 20438, 6477
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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