Invitrogen™ SIAH1 Polyclonal Antibody, Biotin

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5141996

Catalog No. PIPA5141996

Description

Additional Information: This antibody is expected to recognize both reported isoforms (NP_003022.3; NP_001006611.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

This gene encodes a protein that is a member of the seven in absentia homolog family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Specifications

• Antigen: SIAH1
• Classification: Polyclonal
• Conjugate: Biotin
• Gene: SIAH1
• Gene Alias: AA960570; AA982064; AI853500; E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase SIAH1A; E3 ubiquitin-protein ligase SIAH1B; FLJ08065; h HUMSIAH; hSIAH1; HUMSIAH; mSiah-1a; RING-type E3 ubiquitin transferase SIAH1; RING-type E3 ubiquitin transferase SIAH1A; RING-type E3 ubiquitin transferase SIAH1B; seven in absentia 1A; seven in absentia 1B; seven in absentia homolog 1; Seven in absentia homolog 1a; Seven in absentia homolog 1b; SIAH; siah E3 ubiquitin protein ligase 1; SIAH1; siah-1; Siah1a; Siah-1a; Siah1b; siah-1b; Sinh1a; Sinh1b
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 110337437, 140941, 20437, 20438, 6477
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P61092, Q06985, Q8IUQ4, Q920M9
• Gene Symbols: SIAH1, Siah1a, Siah1b
• Immunogen: Peptide with sequence SRQTATALPTGTSKC (aa 2-16).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG