Invitrogen™ Sialosyl-Tn Antigen Monoclonal Antibody (STn 219)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA190577

Catalog No. MA190577

Description

Recommended positive controls: Human gastrointestinal tumor, prostate, ovary ca.. This antibody stains colon carcinomas and ovarian mucinous carcinomas producing apical cytoplasmic, apical membrane and luminal staining patterns. It is negative with majority of adult tissue sections.

Sialosyl Tn antigen, also known as CD175s, is expressed in the majority of colon, gastric, breast, and lung carcinoma. The sialosyl Tn has limited expression to being absent in normal colon, pancreas, stomach, ovary, and prostate. This antigen is detected in several adenocarcinomas. It appears to be useful marker for poorly differentiated colon adenocarcinoma.

Specifications

• Antigen: Sialosyl-Tn Antigen
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Human, Sheep
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: STn 219
• Conjugate: Unconjugated
• Gene Alias: CD175s
• Immunogen: Ovine submaxillary mucin (OSM).
• Quantity: 500 μL
• Primary or Secondary: Primary
• Content And Storage: 4°C, do not freeze
• Form: Liquid