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Tocris Bioscience™ SIB 1893 Available on GSA/VA Contract for Federal Government customers only.

mGlu5 antagonist; also positive allosteric modulator at mGlu4 receptors

Manufacturer:  Tocris Bioscience™ 1214/10

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Catalog No. 12-141-0


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Description

Description

A highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. Centrally active upon systemic administration in vivo. Positive allosteric modulator at mGlu4 receptors.

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Specifications

Specifications

SIB 1893
SIB 1893
195.26
10mg
SDS
Documents
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