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Tocris Bioscience™ SIB 1893

Catalog No. 121410
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10 mg
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Catalog No. Quantity
12-141-0 10 mg
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Catalog No. 12-141-0 Supplier Tocris Bioscience™ Supplier No. 1214/10

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Description

mGlu5 antagonist; also positive allosteric modulator at mGlu4 receptors

SIB 1893 is an a highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. Centrally active upon systemic administration in vivo. Positive allosteric modulator at mGlu4 receptors.

Specifications

Quantity 10 mg
Product Type SIB 1893
Molecular Weight (g/mol) 195.26
Inhibitors SIB 1893

For Research Use Only

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