Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. N234511PEC7

Siglec-3/CD33 Antibody (WM53), PE/Cy7, Novus Biologicals™
SDP

Catalog No. N234511PEC7 Shop All R&D Systems Products
Change view
Click to view available options
Quantity:
0.1 mL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
N234511PEC7 0.1 mL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. N234511PEC7 Supplier Novus Biologicals Supplier No. NBP234511PECY7
Only null left
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

Siglec-3/CD33 Monoclonal specifically detects Siglec-3/CD33 in Human samples. It is validated for Flow Cytometry.

Specifications

Antigen Siglec-3/CD33
Applications Flow Cytometry
Classification Monoclonal
Clone WM53
Conjugate PE-Cyanine7
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Gene Symbols CD33
Host Species Mouse
Immunogen Human AML cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Immunology
Primary or Secondary Primary
Gene ID (Entrez) 945.0
Test Specificity Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Target Species Human
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG1 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.