Invitrogen™ SIGLEC5 Polyclonal Antibody

Catalog No.	Quantity
PIPA547058	100 μg

Catalog No. PIPA547058 Supplier Invitrogen™ Supplier No. PA547058

Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) Siglec-7 and rhSiglec-9 is observed and less than 1% cross-reactivity with rhSiglec-2 and rhSiglec-3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

SIGLEC5 (CD170) is a member of the sialic acid-binding immunoglobulin-like lectin family expressed mainly on myeloid cells such as neutrophils and monocytes. It functions as an inhibitory receptor that recognizes sialylated glycans and transduces signals through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail, helping regulate innate immune responses and dampen inflammation.

Specifications

• Antigen: SIGLEC5
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Neutralization, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: SIGLEC5
• Gene Accession No.: O15389
• Gene Alias: CD170
• Gene Symbols: SIGLEC5
• Host Species: Goat
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Siglec-5 Glu17-Thr434.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8778
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG