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Invitrogen™ SIGLEC5 Polyclonal Antibody
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Catalog No. PIPA5110370
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100 μL
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PIPA5110370 100 μL
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Catalog No. PIPA5110370 Supplier Invitrogen™ Supplier No. PA5110370
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EKPVYELQVQ KSVTVQEGLC VLVPCSFSYP WRSWYSSPPL YVYWFRDGEI PYYAEVVATN NPDRRVKPET QGRFRLLGDV QKKNCSLSIG DARMEDTGSY FFRVERGRDV KYSYQQNKLN LEVTALIEKP DIHFLEPLES GRPTRLSCSL PGSCEAGPPL TFSWTGNALS PLDPETTRSS ELTLTPRPED HGTNLTCQMK RQGAQVTTER TVQLNVSYAP QTITIFRNGI ALEILQNTSY LPVLEGQALR LLCDAPSNPP AHLSWFQGSP ALNATPISNT GILELRRVRS AEEGGFTCRA QHPLGFLQIF LNLSVYSLPQ LLGPSCSWEA EGLHCRCSFR ARPAPSLCWR LEEKPLEGNS SQGSFKVNSS SAGPWANSSL ILHGGLSSDL KVSCKAWNIY GSQSGSVLLL QGRSNLGT.

SIGLEC5 (CD170) is a member of the sialic acid-binding immunoglobulin-like lectin family expressed mainly on myeloid cells such as neutrophils and monocytes. It functions as an inhibitory receptor that recognizes sialylated glycans and transduces signals through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail, helping regulate innate immune responses and dampen inflammation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIGLEC5
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4.51 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene SIGLEC5
Gene Accession No. O15389
Gene Alias CD170
Gene Symbols SIGLEC5
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 17-434 of human SIGLEC5 (NP_0038211).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8778
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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