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Invitrogen™ SIGLEC7 Polyclonal Antibody

Rabbit Polyclonal Antibody

$178.40 - $511.50

Specifications

Antigen SIGLEC7
Concentration 500 μg/mL
Content And Storage -20°C
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIPA5119414
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Invitrogen™
PA5119414
200 μL
Each for $511.50
Only null left
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PIPA5122116
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Invitrogen™
PA5122116
20 μL
Each for $178.40
Only null left
Add to Cart
 
Description

Description

SIGLEC7 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Specifications

Specifications

SIGLEC7
-20°C
Polyclonal
Liquid
IgG
Human
SIGLEC7
Adhesion inhibitory receptor molecule 1; adhesion inhibitory receptor molecule 1, siglec-7; AIRM1; AIRM-1; CD328; CDw328; D-siglec; p75; p75/ AIRM-1; p75/AIRM1; QA79; QA79 membrane protein; sialic acid binding Ig like lectin 7; sialic acid binding Ig-like lectin 7; sialic acid binding immunoglobulin-like lectin 7; sialic acid-binding Ig-like lectin 7; Siglec; SIGLEC19P; SIGLEC7; SIGLEC-7; SIGLECP2
SIGLEC7
Primary
Antigen affinity chromatography
500 μg/mL
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Unconjugated
Rabbit
RUO
PBS with 50% glycerol and 0.05% ProClin 300
Q9Y286
27036
Recombinant protein Sialic Acid Binding Ig Like Lectin 7. The antigen corresponds to amino acid range 18-353 of the target protein.
Antibody
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