SIGLEC9 Mouse anti-Human, Clone: OTI1D9, liquid, TrueMAB™

Catalog No.	Quantity
50-167-1512	100 μL

Catalog No. 50-167-1512 Supplier OriGene Supplier No. TA500379

Description

Mouse Monoclonal Antibody

Siglec9 (Sialic acid-binding Ig-like lectin 9) is single-pass type I membrane protein and belongs to immunoglobulin super family and contains two Ig-like C2 type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is reported that Siglec9 recognizes sialic acid in alpha2, 3-or alpha2, 6-glycosidic linkage to galactose. Using a specific antibody, Siglec9 was found to be expressed at high or intermediate levels by monocytes, neutrophils, and a minor population of CD16+, CD56- cells. Siglec9 also acts as an inhibitory receptor for MUC16 that attenuates T- andNK cell function. Recent reports suggest that Siglec9 expressed on DCs is involved in immuno regulation through ligation with mucins in an epithelial cancer patient.

Specifications

• Antigen: SIGLEC9
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI1D9
• Concentration: 0.7 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: SIGLEC9
• Gene Accession No.: Q9Y336
• Gene Alias: CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9
• Gene Symbols: SIGLEC9
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human SIGLEC9 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 27180
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1